(1,5-DIMETHYL-1H-PYRAZOL-3-YL)METHYLAMINE Chemical Properties

Boiling point:

94 °C

Density 

1.12±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

8.26±0.29(Predicted)

form 

liquid

color 

Colourless to light yellow

Safety Information

Hazard Codes 

C

Hazard Note 

Corrosive

HS Code 

2933199090

(1,5-DIMETHYL-1H-PYRAZOL-3-YL)METHYLAMINE Usage And Synthesis

Synthesis

1,5-Dimethyl-1H-pyrazole-3-carboxamide was used as starting material and dissolved in 70 mL of tetrahydrofuran (THF) at 0 °C. Subsequently, lithium aluminum hydride (LiAlH4, 4.1 g, 107.89 mmol) was added in batches. The reaction mixture was heated to reflux for 1 hour. Upon completion of the reaction, solid impurities were removed by filtration and the filtrate was concentrated to afford (1,5-dimethyl-1H-pyrazol-3-yl)methanamine in the form of a yellow oil in a yield of 3 g and 67%.

References

[1] Patent: WO2009/139834, 2009, A1. Location in patent: Page/Page column 129

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