ETHYL 4-PHENYLBUTYRATE Chemical Properties

Boiling point:

100°C/1mmHg(lit.)

Density 

1.001 g/cm3

refractive index 

1.4910 to 1.4950

FEMA 

2453 | ETHYL 4-PHENYLBUTYRATE

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Oil

color 

Colourless

Odor

at 10.00 % in dipropylene glycol. sweet fruity plum

Odor Type

fruity

JECFA Number

1458

LogP

3.30

Safety Information

HS Code 

2916.39.7900

ETHYL 4-PHENYLBUTYRATE Usage And Synthesis

Chemical Properties

Ethyl 4-phenylbutyrate has a sweet, fruity, plum-like odor and cooked plum–prune taste.

Uses

Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.

Definition

ChEBI: Ethyl 4-phenylbutanoate is a fatty acid ester.

Application

Ethyl-4-phenylbutanoate is probably used in flavors only. It imparts at a very low concentrations a certain amount of “natural” body and richness to many berries and other fruit flavours. The concentration used in such flavors is equivalent to about 0.06 to 1 ppm in the finished products.

Preparation

By esterification of ethanol with γ-phenylbutyric acid obtained by Grignard reaction from γ-bromopropylbenzene.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 1429, 1985 DOI: 10.1021/ja00291a063

ETHYL 4-PHENYLBUTYRATE(10031-93-3)Related Product Information

• Ethyl 2-oxo-4-phenylbutyrate
• 2,4,6-TRICHLOROPHENYL ISOTHIOCYANATE
• 1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID ETHYL ESTER
• Enalapril maleate
• Ethyl (R)-2-hydroxy-4-phenylbutyrate
• ETHYL 4-PHENYLBUTYRATE
• ETHYL 3-(4-METHOXYBENZOYL)PROPIONATE
• STYRENE MALEIC ANHYDRIDE COPOLYMER
• 2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate
• ethyl 4-bromo-4-phenyl-butanoate
• ethyl 2-phenylbutyrate
• DL-Ethyl 2-bromobutyrate
• Ethyl butyrate
• 4-Phenylbutyric acid
• 1,3-dichloro-2-isothiocyanato-4-methylbenzene
• 4-(2,5-DIOXOTETRAHYDROFURAN-3-YL)-1,2,3,4-TETRAHYDRONAPHTHALENE-1,2-DICARBOXYLIC ANHYDRIDE
• 3,4-DIHYDRO-1,2-NAPHTHALENEDICARBOXYLIC ANHYDRIDE
• DIETHYL 2-(PHENYLETHYL)MALONOATE