6-tert-Butyl-2,3-naphthalenedicarbonitrile Chemical Properties

Melting point:

185-189 °C(lit.)

Boiling point:

429.7±33.0 °C(Predicted)

Density 

1.11±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)

form 

Solid

color 

Pale Yellow to Light Beige

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

6-tert-Butyl-2,3-naphthalenedicarbonitrile Usage And Synthesis

Uses

6-tert-Butyl-2,3-naphthalenedicarbonitrile is a stain with bioloigcal research applications. Dyes and metabolites.

Definition

ChEBI: 6-tert-butylnaphthalene-2,3-dicarbonitrile is a member of naphthalenes.

Biological Activity

BRD9876 is an inhibitor of the kinesin spindle protein Eg5. It arrests Eg5-mediated microtubule gliding, as well as inhibits Eg5 ATPase activity in the presence of microtubules, in cell-free assays. BRD9876 is cytotoxic to MM.1S stroma-independent multiple myeloma cells (IC50 = 2.2 μM). It induces cell cycle arrest at the G2/M phase in MM.1S cells when used at a concentration of 10 μM.

6-tert-Butyl-2,3-naphthalenedicarbonitrile(32703-82-5)Related Product Information

• 2-ETHYL-6-METHYLNAPHTHALENE
• Phthalonitrile
• 2,3,6-TRIMETHYLNAPHTHALENE
• 1,4-Pentadien-3-ol
• 2,7-DIMETHYLNAPHTHALENE
• 2-Naphthonitrile
• 6-tert-Butyl-2,3-naphthalenedicarbonitrile
• 3,3,6,6-Tetramethoxy-1,4-cyclohexadiene
• 2,3-Dicyanonaphthalene
• 2-tert-butylnaphthalene
• 2,6-DIMETHYLNAPHTHALENE