Basic information Safety Supplier Related

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide

Basic information Safety Supplier Related

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide Basic information

Product Name:
(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide
Synonyms:
  • vildagliptin Impurity I
  • -1-(2-Chloroacetyl)
  • (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide
  • (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide
  • 2-PyrrolidinecarboxaMide,1-(2-chloroacetyl)-, (2S)-
  • Vildagliptin Impurity 55
  • Vildagliptin Impurity 8/Vildagliptin Chloroacetyl Amide (S)-Isomer/(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide
  • Vildagliptin?Chloroacetyl Amide (S)-Isomer
CAS:
214398-99-9
MF:
C7H11ClN2O2
MW:
190.63
EINECS:
1308068-626-2
Mol File:
214398-99-9.mol
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(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide Chemical Properties

Melting point:
133-137℃ (isopropyl ether )
Boiling point:
442.5±45.0 °C(Predicted)
Density 
1.353±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Very Slightly)
form 
Solid
pka
15.56±0.20(Predicted)
color 
White to Pale Beige
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Safety Information

HS Code 
2924190090
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(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxaMide Usage And Synthesis

Uses

(S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide is used in the synthesis of Vildagliptin (V305000), an oral anti-diabetic drug, and its impurities (H971380) (Impurity A).

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