ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > DNA damage > DNA / RNA Synthesis inhibitors > BMH21
BMH21
BMH21 Basic information
- Product Name:
- BMH21
- Synonyms:
-
- BMH21
- N-[2-(dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
- BMH-21 N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
- N-[2-(Dimethylamino)ethyl]-12-oxo-2H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
- CS-1749
- BMH 21;BMH21
- BMH-21, >98%
- 12H-Benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide, N-[2-(dimethylamino)ethyl]-12-oxo-
- CAS:
- 896705-16-1
- MF:
- C21H20N4O2
- MW:
- 360.41
- EINECS:
- 809-833-1
- Product Categories:
-
- Inhibitors
- Mol File:
- 896705-16-1.mol
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BMH21 Chemical Properties
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble1mg/mL, clear (warmed)
- pka
- 7.90±0.20(Predicted)
- form
- powder
- color
- light yellow to dark yellow
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BMH21 Usage And Synthesis
Uses
BMH-21 has been used in cell culture.
General Description
BMH-21 is a planar heterocyclic small molecule DNA intercalator.
Biochem/physiol Actions
BMH-21 is a potent inhibitor of RNA Pol I. BMH-21 binds strongly to GC-rich DNA sequences, ultimately inhibiting RNA Pol I, blocking transcription and disrupting the nucleolar structure. BMH-1 causes dissociation of the RPA194 catalytic subunit from Pol I, and disassembly of Pol I:DNA complexes. The compound BMH-21 inhibits proliferation of a broad range of tumor cell lines.
storage
Store at -20°C
BMH21Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
AdooQ BioScience, LLC
- Tel
- +1 (866) 930-6790
- info@adooq.com
TargetMol Chemicals Inc.
- Tel
- 021-33632979 15002134094
- marketing@targetmol.com