m-PEG10-Tos
m-PEG10-Tos Basic information
- Product Name:
- m-PEG10-Tos
- Synonyms:
-
- m-PEG10-OTs
- m-PEG10-Tos
- 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol, 1-(4-methylbenzenesulfonate)
- 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 4-methylbenzenesulfonate
- nonaethylene glycol methyl tosyl ether
- TosO-(CH2CH2O)9-Me
- CAS:
- 211859-75-5
- MF:
- C26H46O12S
- MW:
- 582.7
- Mol File:
- 211859-75-5.mol
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m-PEG10-Tos Chemical Properties
- Boiling point:
- 627.7±55.0 °C(Predicted)
- Density
- 1.146±0.06 g/cm3(Predicted)
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m-PEG10-Tos Usage And Synthesis
Description
m-PEG10-Tos is a PEG linker containing a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG10-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Jennifer Riggs-Sauthier, et al. Oligomer-opioid agonist conjugates. US8575196B2.
m-PEG10-TosSupplier
Nanjing Junnahe Biopharmaceutical Co., Ltd
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