ELASTASE SUBSTRATE IV, COLORIMETRIC Chemical Properties

storage temp. 

Store at -20°C

solubility 

ethanol: 1mg/mL
water: soluble

form 

lyophilized solid

color 

white to off-white

Water Solubility 

Water: 1 mg/ml

ELASTASE SUBSTRATE IV, COLORIMETRIC Usage And Synthesis

Uses

Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration[1].

Biological Activity

Cell permeable: no', 'Primary Target
A specific substrate for pancreatic elastase', 'Product does not compete with ATP.', 'Reversible: no', 'km = 100 μM; kcat/ Km = 35,000 M-1 s-1 for r at pancreatic elastase; Km = 30 μM; kcat/Km = 35,000 M-1 s-1 for porcine

References

[1] Largman C. Isolation and characterization of rat pancreatic elastase. Biochemistry. 1983 Aug 2;22(16):3763-70. DOI:10.1021/bi00285a008

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