ROSE BENGAL LACTONE CAS#: 4159-77-7

ROSE BENGAL LACTONE Basic information

Product Name:

ROSE BENGAL LACTONE

Synonyms:

4’,5’,7’-tetraiodo-droxy-2
spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy
ROSE BENGAL LACTONE
4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
Solvent Red 141

CAS:

4159-77-7

MF:

C20H4Cl4I4O5

MW:

973.67

EINECS:

223-993-4

Product Categories:

Q-R
Stains and Dyes
Stains&Dyes, A to

Mol File:

4159-77-7.mol

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ROSE BENGAL LACTONE Chemical Properties

Melting point:: 280 °C (dec.)(lit.)
storage temp.: room temp
Boiling point:: 741.8±60.0 °C(Predicted)
Density: 2.96±0.1 g/cm3(Predicted)
pka: 7.03±0.20(Predicted)
form: powder
color: pink to red
λmax: 557 nm
ε(extinction coefficient): ≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm
EPA Substance Registry System: Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- (4159-77-7)

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Safety Information

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3

MSDS

Language:English Provider:SigmaAldrich

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ROSE BENGAL LACTONE Usage And Synthesis

Description

Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol.

Chemical Properties

Bluish-pink powder. Soluble in water.

Uses

Biological stain; colorant for inks, cellulosics, foods, cosmetics, medicine (diagnostic aid).

Preparation

will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide.

Properties and Applications

blue light red. Soluble in water for blue light yellow, no fluorescence, in concentrated sulfuric acid for brown, dilution after hot pink precipitation. Used in cosmetics coloring.

Standard	Light Fastness	Heat-resistant(℃)		water	Sodium Carbonate(5%)	Hydrochloric acid(5%)
		Melting point	Stable
ISO	Poor			Insoluble

ROSE BENGAL LACTONESupplier

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Email: sales8178@energy-chemical.com

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Email: product02@bidepharm.com

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Email: sales@xiyashiji.com

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）

Henan Alpha Chemical Co., Ltd.

Tel: 0371-0371-55055611 18137792234
Email: 3002694073@qq.com

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