Basic information Safety Supplier Related

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid

Basic information Safety Supplier Related

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Basic information

Product Name:
(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid
Synonyms:
  • (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid
  • Boc-Val-Cit-OH
  • Boc-Val-Cit
  • L-Ornithine, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-
  • (R)-2-((R)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid
  • Boc-L-valyl-L-citrulline
  • ADC Linkers,Inhibitor,Boc Val Cit OH,BocValCitOH,Antibody-drug conjugates linkers,inhibit
  • N-Boc-L-valyl-N5-(aminocarbonyl)-L-ornithine
CAS:
870487-08-4
MF:
C16H30N4O6
MW:
374.43
Product Categories:
  • Linker
  • ADC LINKER
Mol File:
870487-08-4.mol
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(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Chemical Properties

Boiling point:
624.8±55.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
solubility 
Soluble in DMSO
pka
3.44±0.10(Predicted)
form 
Solid
color 
White to off-white
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(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Usage And Synthesis

Description

Boc-Val-Cit is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition.

(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acidSupplier

Kanghua (Shanghai) New Drug Development Co., Ltd. Gold
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021-61263370 18901917034
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xingli@glbiochem.com
PharmaBlock Sciences (Nanjing),Inc.
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025-86918202 4000255188
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Sichuan Tongsheng Amino acids Co.,Ltd.
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Accela ChemBio Co.,Ltd.
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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