2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Chemical Properties

Boiling point:

424.5±30.0 °C(Predicted)

Density 

1.129±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly

form 

A crystalline solid

color 

Light yellow to yellow

Safety Information

HS Code 

2926907090

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Usage And Synthesis

Description

O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.

Uses

O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.

2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE(175135-47-4)Related Product Information

• {4-[(3-methoxybenzyl)oxy]phenyl}acetonitrile
• 4-ETHOXYPHENYLACETONITRILE
• 4-Benzyloxyphenylacetonitrile
• 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE
• 4-Methoxybenzyl cyanide
• 4-Hydroxybenzyl cyanide