Basic information Safety Supplier Related

THIOLACTOMYCIN

Basic information Safety Supplier Related

THIOLACTOMYCIN Basic information

Product Name:
THIOLACTOMYCIN
Synonyms:
  • (r-(e))-3,5-dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-2(5h)-thiophenone
  • Antibiotic 2-200, [R-(E)]-4-Hydroxy-3,5-dimethyl-5-(2-methyl-1,3-butadienyl)-2(5H)-thiophenone, (5R)-4-Hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadienyl]-2(5H)-thiophenone
  • (S)-4-Hydroxy-3,5-dimethyl-5-[(2E)-2-methyl-1,3-butadienyl]thiophen-2(5H)-one
  • (S)-4-Hydroxy-3,5-dimethyl-5-[(E)-2-methyl-1,3-butadienyl]thiophen-2(5H)-one
  • 3,5-dimethyl-4-hydroxy-5-(2-methyl-1,3-butadienyl)-2(5h)-thiophenon(r-(e))
  • SYQNUQSGEWNWKV-XUIVZRPNSA-N
  • 2(5H)-Thiophenone, 4-hydroxy-3,5-dimethyl-5-[(1E)-2-methyl-1,3-butadien-1-yl]-, (5R)-
  • Thiolactomycin, 96+%
CAS:
82079-32-1
MF:
C11H14O2S
MW:
210.29
Mol File:
82079-32-1.mol
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THIOLACTOMYCIN Chemical Properties

solubility 
DMSO: ~21 mg/mL, soluble
form 
solid
color 
light yellow
Stability:
Light Sensitive
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Safety Information

WGK Germany 
3
RTECS 
XN1928870
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THIOLACTOMYCIN Usage And Synthesis

Uses

(R)-(+)-Thiolactomycin is a natural product inhibitor of β-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).

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