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Ezetimibe-28

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Ezetimibe-28 Basic information

Product Name:
Ezetimibe-28
Synonyms:
  • Ezetimibe Impurity 73
  • Ezetimibe-28
  • Ezetimibe impuriry 27/(S)-3-((R)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-4-(2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one
  • (S)-3-((R)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-4-(2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one
  • Ezetimibe Impuriry 73
  • 2-Oxazolidinone, 3-[(2R)-2-[(S)-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-, (4S)-
  • Ezetimibe Impurity U
CAS:
1478663-95-4
MF:
C44H52F2N2O6Si
MW:
770.98
Mol File:
1478663-95-4.mol
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Ezetimibe-28 Chemical Properties

Boiling point:
793.6±60.0 °C(Predicted)
Density 
1.178±0.06 g/cm3(Predicted)
pka
3.31±0.50(Predicted)
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Ezetimibe-28 Usage And Synthesis

Uses

(4S)-3-[(2R)-2-[(S)-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl][(4-fluorophenyl)amino]methyl]-4-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of (3’R,3R,4R)-Ezetimibe (E974990), a structural analog of Ezetimibe (E975000). Ezetimibe is an antihyperlipoproteinemic and a cholesterol absorption inhibitor.

Ezetimibe-28Supplier

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