6-HYDROXY-2-METHYLAMINOPURINE Chemical Properties

Melting point:

>300 °C (decomp)

Density 

1.79±0.1 g/cm3(Predicted)

storage temp. 

4°C, Inert atmosphere

solubility 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

form 

Solid

pka

9.86±0.20(Predicted)

color 

Light yellow to khaki

6-HYDROXY-2-METHYLAMINOPURINE Usage And Synthesis

Uses

2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.

Definition

ChEBI: N(2)-methylguanine is a methylguanine in which the methyl group is located at the N2-position. It has a role as a human metabolite. It is a methylguanine and a secondary amino compound.

IC 50

Human Endogenous Metabolite

References

[1] Rife JP, et al. N 2-methylguanosine is iso-energetic with guanosine in RNA duplexes and GNRA tetraloops. Nucleic Acids Res. 1998 Aug 15;26(16):3640-4. DOI:10.1093/nar/26.16.3640
[2] Youvan DC, et al. Reverse transcriptase pauses at N2-methylguanine during in vitro transcription of Escherichia coli 16S ribosomal RNA. Proc Natl Acad Sci U S A. 1979 Aug;76(8):3751-4. DOI:10.1073/pnas.76.8.3751

6-HYDROXY-2-METHYLAMINOPURINE(10030-78-1)Related Product Information

• Guanine
• Oxipurinol
• (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
• NU6140
• 6-HYDROXY-2-METHYLAMINOPURINE
• 2-((4-Butylphenyl)amino)-6-methoxy-9H-purine
• 2-DIMETHYLAMINO-6-HYDROXYPURINE
• DIPHENYL-CARBAMIC ACID(2-ISOBUTYRYL GUANINE) ESTER
• N2-ACETYL-O6-(DIPHENYLCARBAMOYL)GUANINE
• N2-acetamido-6-benzyloxypurine
• N,9-Diacetylguanine
• 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine
• NU6102