2-(Trifluoromethyl)pyridine Chemical Properties

Boiling point:

139-141 °C

Density 

1.275 g/mL at 25 °C

refractive index 

n20/D 1.419

Flash point:

109 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in most organic solvents.

pka

0.60±0.12(Predicted)

form 

clear liquid

color 

Colorless to Light yellow

BRN 

3112

InChIKey

ATRQECRSCHYSNP-UHFFFAOYSA-N

CAS DataBase Reference

368-48-9(CAS DataBase Reference)

NIST Chemistry Reference

2-(CF3)-pyridine(368-48-9)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

10-36/37/38

Safety Statements 

16-26-36

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard Note 

Flammable/Irritant

HazardClass 

3

PackingGroup 

III

HS Code 

2933399990

MSDS

• Language:English Provider:2-(Trifluoromethyl)pyridine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-(Trifluoromethyl)pyridine Usage And Synthesis

Uses

Lithiation with n-BuLi/LiOCH2CH2NMe2?takes place at the 6-position, affording access to 6-substituted derivatives. With LiTMP?. It is a building block in heterocycle synthesis.

Synthesis Reference(s)

Synthesis, p. 932, 1980 DOI: 10.1055/s-1980-29276

2-(Trifluoromethyl)pyridine(368-48-9)Related Product Information

• Trifluoromethanesulfonic acid
• 2,6-Lutidine
• 3-Trifluoromethylpyridine
• Azamethiphos
• 2,4,6-Collidine
• 2-(Trifluoromethyl)benzoic acid
• 4-Methylpyridine
• 3-(Trifluoromethyl)benzaldehyde
• 3-Aminobenzotrifluoride
• Pyridine
• 4-(Trifluoromethyl)pyridine
• 7-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE
• 3-BROMO-5-(TRIFLUOROMETHYL)PYRIDINE
• 2,8-BIS(TRIFLUOROMETHYL)-4-BROMOQUINOLINE
• 2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE
• 2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE
• 2,8-Bis(trifluoromethyl)-4-quinolinol
• 3,4-BIS(TRIFLUOROMETHYL)PYRIDINE