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CINCHOPHEN

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CINCHOPHEN Basic information

Product Name:
CINCHOPHEN
Synonyms:
  • LABOTEST-BB LT00453769
  • RHEUMIN
  • RHEMATAN
  • 2-PHENYLQUINOLINE-4-CARBOXYLIC ACID
  • 2-PHENYLQUINOLEINE-4-CARBOXYLIC ACID
  • 2-PHENYLCINCHONINIC ACID
  • 2-PHENYL-4-QUINOLINECARBOXYLIC ACID
  • CINCHOPHEN
CAS:
132-60-5
MF:
C16H11NO2
MW:
249.26
EINECS:
205-067-1
Product Categories:
  • ATOPHAN
  • API intermediates
  • Quinolinecarboxylic Acids, etc.
  • Quinolines
Mol File:
132-60-5.mol
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CINCHOPHEN Chemical Properties

Melting point:
214-215 °C (lit.)
Boiling point:
392.37°C (rough estimate)
Density 
1.1426 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
alcohol: soluble1g in 120ml(lit.)
pka
0.96±0.10(Predicted)
Water Solubility 
Insoluble in water
Sensitive 
Light Sensitive
Merck 
14,2288
BRN 
192803
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36/37/39-26
RIDADR 
3249
WGK Germany 
3
RTECS 
GD4025000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29334990
Hazardous Substances Data
132-60-5(Hazardous Substances Data)
Toxicity
LD50 oral in dog: 1250mg/kg

MSDS

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CINCHOPHEN Usage And Synthesis

Chemical Properties

BEIGE POWDER

Uses

analgesic, antipyretic, antiinflammatory

brand name

Aglophenyl;Alcophenyl;Artexin;Atophan;Cefeno;Cinchophene;Cinconal;Cincosal;Fenofan;Iriphan;Mylofanol;Mylophanol;Phenoquin;Rhematan;Tervalon;Traubofan;Viophan.

World Health Organization (WHO)

Cinchophen, an analgesic and antipyretic, was formerly available in preparations for the treatment of gout. Its use was associated with adverse effects including hepatitis, cirrhosis, skin lesions and angioneurotic oedema. WHO has no information to suggest that preparations containing cinchophen remains commercially available.

Purification Methods

It crystallises from EtOH (ca 20mL/g), in several modifications with m 196o and 216o(subliming at 65o). [Beilstein 22 H 103, 22 II 518, 22 II 70, 22 III/IV 1358.]

CINCHOPHEN Preparation Products And Raw materials

Raw materials

CINCHOPHENSupplier

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