CINCHOPHEN Chemical Properties

Melting point:

214-215 °C (lit.)

Boiling point:

392.37°C (rough estimate)

Density 

1.1426 (rough estimate)

refractive index 

1.5300 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

alcohol: soluble1g in 120ml(lit.)

pka

0.96±0.10(Predicted)

form 

Solid

color 

White

Water Solubility 

Insoluble in water

Sensitive 

Light Sensitive

Merck 

14,2288

BRN 

192803

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

36/37/39-26

RIDADR 

3249

WGK Germany 

3

RTECS 

GD4025000

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29334990

Hazardous Substances Data

132-60-5(Hazardous Substances Data)

Toxicity

LD50 oral in dog: 1250mg/kg

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

CINCHOPHEN Usage And Synthesis

Chemical Properties

BEIGE POWDER

Uses

analgesic, antipyretic, antiinflammatory

Uses

Cinchophen and its derivatives can show antipyretic, analgesic, anti-oxidative, and anti-inflammatory properties.

Definition

ChEBI: 2-phenyl-4-quinolinecarboxylic acid is a member of quinolines.

brand name

Aglophenyl;Alcophenyl;Artexin;Atophan;Cefeno;Cinchophene;Cinconal;Cincosal;Fenofan;Iriphan;Mylofanol;Mylophanol;Phenoquin;Rhematan;Tervalon;Traubofan;Viophan.

World Health Organization (WHO)

Cinchophen, an analgesic and antipyretic, was formerly available in preparations for the treatment of gout. Its use was associated with adverse effects including hepatitis, cirrhosis, skin lesions and angioneurotic oedema. WHO has no information to suggest that preparations containing cinchophen remains commercially available.

Purification Methods

It crystallises from EtOH (ca 20mL/g), in several modifications with m 196o and 216o(subliming at 65o). [Beilstein 22 H 103, 22 II 518, 22 II 70, 22 III/IV 1358.]

CINCHOPHEN(132-60-5)Related Product Information

• 1(2H)-Phthalazinone, 4-[[3-[[4-(2-ethylbutyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-
• 4-(Aminomethyl)-1(2H)-phthalazinone
• Uridine, 4-oxime, 5'-cyclopropanecarboxylate
• CINCHOPHEN
• 2-(4-CHLORO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• oxycinchophen
• Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate
• QUINOLINE-4-CARBOXYLIC ACID
• 2-Phenylquinoline
• 2-(4-AMINO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• 6-CHLORO-2-(4-CHLOROPHENYL)-4-QUINOLINE CARBOXYLIC ACID
• 2-(3-AMINO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• 2-(4-METHOXY-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• 2-P-TOLYL-QUINOLINE-4-CARBOXYLIC ACID
• 2-PHENYL-QUINOLINE-4-CARBOXYLIC ACID METHYL ESTER
• 6-BROMO-2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
• 6-BROMO-2-P-TOLYL-QUINOLINE-4-CARBOXYLIC ACID
• 6-METHOXY-2-PHENYL-4-QUINOLINECARBOXYLIC ACID