Vorsetuzumab
Vorsetuzumab Basic information
- Product Name:
- Vorsetuzumab
- Synonyms:
-
- Vorsetuzumab
- Research Grade Vorsetuzumab(DHE01902)
- Vorsetuzumab (anti-CD70)
- SGN-70
- Research Grade Vorsetuzumab
- CAS:
- 1165740-62-4
- MW:
- 0
- Mol File:
- Mol File
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Vorsetuzumab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Vorsetuzumab Usage And Synthesis
Uses
Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a human anti-CD70 antibody. Vorsetuzumab enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma[1].
in vivo
Vorsetuzumab (10 mg/kg; i.p.; every other day; for 12 d) inhibits Burkitt’s lymphoma cell growth growth in SRG mice[1].
| Animal Model: | Burkitt’s lymphoma xenograft model in SRG mice[1] |
| Dosage: | 10 mg/kg |
| Administration: | Intraperitoneal injection; every other day; for 12 d |
| Result: | Effectively inhibited Burkitt’s lymphoma cell growth but was not outperform the combination of the KWAR23 antibody (10 mg/kg). |
References
[1] Ring NG, et al. Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585. DOI:10.1073/pnas.1710877114
VorsetuzumabSupplier
Shanghai YuanYe Biotechnology Co., Ltd.
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- 021-61312847; 18021002903
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ShangHai Biochempartner Co.,Ltd
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- 177-54423994 17754423994
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Wuhan Chemstan Biotechnology Co., Ltd.
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- 027-65317797 15926423062
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TargetMol Chemicals Inc.
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- 4008200310
- marketing@tsbiochem.com
Biolab Reagents
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