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Vorsetuzumab

Product Name
Vorsetuzumab
CAS No.
1165740-62-4
Chemical Name
Vorsetuzumab
Synonyms
SGN-70;Vorsetuzumab;Vorsetuzumab (anti-CD70);Research Grade Vorsetuzumab;Research Grade Vorsetuzumab(DHE01902)
CBNumber
CB88080868
Formula Weight
0
MOL File
Mol file
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Vorsetuzumab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Vorsetuzumab Chemical Properties,Usage,Production

Uses

Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a human anti-CD70 antibody. Vorsetuzumab enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma[1].

in vivo

Vorsetuzumab (10 mg/kg; i.p.; every other day; for 12 d) inhibits Burkitt’s lymphoma cell growth growth in SRG mice[1].

Animal Model:Burkitt’s lymphoma xenograft model in SRG mice[1]
Dosage:10 mg/kg
Administration:Intraperitoneal injection; every other day; for 12 d
Result:Effectively inhibited Burkitt’s lymphoma cell growth but was not outperform the combination of the KWAR23 antibody (10 mg/kg).

References

[1] Ring NG, et al. Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585. DOI:10.1073/pnas.1710877114

Vorsetuzumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Vorsetuzumab Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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China
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71826
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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8000
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Wuhan Chemstan Biotechnology Co., Ltd.
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027-65317797 15926423062
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QQ:422450190
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422450190@qq.com
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China
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10308
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
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58
Biolab Reagents
Tel
027-65279366 18108604356
Email
products@biolabreagent.com
Country
China
ProdList
9868
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Wuhan Jingkangen Biomedical Technology Co., Ltd
Tel
13720134139 086-15871494362 13720134139
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orders@jknbiochem.com
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China
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Nantong QuanYi Biotechnology Co., Ltd
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Shanghai Yifei Biotechnology Co. , Ltd.
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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Changsha Fuzhen Biotechnology Co.,LTD
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0731-13823398 15111215862
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1165740-62-4, VorsetuzumabRelated Search:


  • Vorsetuzumab
  • Research Grade Vorsetuzumab(DHE01902)
  • Vorsetuzumab (anti-CD70)
  • SGN-70
  • Research Grade Vorsetuzumab
  • 1165740-62-4