Bedinvetmab
Bedinvetmab Basic information
- Product Name:
- Bedinvetmab
- Synonyms:
-
- Bedinvetmab
- Research Grade Bedinvetmab (DQB91701)
- Research Grade Bedinvetmab
- CAS:
- 2171034-69-6
- MW:
- 0
- Mol File:
- Mol File
Bedinvetmab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
Bedinvetmab Usage And Synthesis
Uses
Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs[1][2].
in vivo
Bedinvetmab (0.5-1 mg/kg; s.c. for 28 d) alleviates the pain associated with canine osteoarthritis[1].
Bedinvetmab (1 mg/kg; s.c. monthly; 3× and 10× dose multiples) is well tolerated in normal laboratory Beagle dogs for 6 months and with 2 weeks' concurrent NSAID administration[2].
References
[1] Corral MJ, et, al. A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab, a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis. Vet Anaesth Analg. 2021 Nov;48(6):943-955. DOI:10.1016/j.vaa.2021.08.001
[2] Krautmann M, et, al. Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs. Vet J. 2021 Oct;276:105733. DOI:10.1016/j.tvjl.2021.105733
BedinvetmabSupplier
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
- Tel
- 027-65317797 15926423062
- 422450190@qq.com
- Tel
- 027-65279366 18108604356
- products@biolabreagent.com
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com