4-(4-(4-Nitrophenyl)-1-piperazinyl)phenol Chemical Properties

Melting point:

>90°C (dec.)

Boiling point:

540.8±50.0 °C(Predicted)

Density 

1.317±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly, Heated)

pka

12.18±0.30(Predicted)

form 

Solid

color 

Yellow to Brown

InChI

InChI=1S/C16H17N3O3/c20-16-7-5-14(6-8-16)18-11-9-17(10-12-18)13-1-3-15(4-2-13)19(21)22/h1-8,20H,9-12H2

InChIKey

BNHYDULILNJFFY-UHFFFAOYSA-N

SMILES

C1(O)=CC=C(N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2)C=C1

CAS DataBase Reference

112559-81-6(CAS DataBase Reference)

4-(4-(4-Nitrophenyl)-1-piperazinyl)phenol Usage And Synthesis

Uses

4-[4-(4-Nitrophenyl)-1-piperazinyl]phenol is a key intermediate in the synthesis of triazole medicines, such as itraconazole (I937500), which are used in curing deep department fungal infections. Inhibitor of endothelial cell proliferation.

4-(4-(4-Nitrophenyl)-1-piperazinyl)phenol(112559-81-6)Related Product Information

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• Posaconazole Impurity 50
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• 2-Aminophenol
• 1-Phenyl-2-nitropropene
• Phenol
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• 4-Nitrophenol
• 3-Aminophenol
• 1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene
• PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
• 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,
• Posaconazole Impurity 64
• Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI)
• 1-(4-Methoxyphenyl)piperazine