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Phenol Red

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Phenol Red Basic information

Product Name:
Phenol Red
Synonyms:
  • PHENOL REDRESEARCH GRADE
  • A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE
  • 3,3-BIS(P-HYDROXYPHENYL)-2,1-3H-BENZOXATHIOLE
  • SULFONAPHTHAL
  • TIMTEC-BB SBB006473
  • PR
  • PHENOSULFOHEPHTHALEIN INDICATOR
  • PHENOLSULFONPHTHALEIN
CAS:
143-74-8
MF:
C19H14O5S
MW:
354.38
EINECS:
205-609-7
Product Categories:
  • Stains and Dyes
  • P
  • Stains&Dyes, A to
  • General Stains/Dyes for Stem Cell BiologyStains and Dyes
  • PReagents and Supplements
  • Cell Culture
  • Analytical Chemistry
  • Indicator (pH)
  • pH Indicators
  • Cell Viability and Proliferation
  • In Vivo/In Vitro Tracking of Stem CellsStem Cell Biology
  • Stains, Dyes and Indicators
  • Stem Cell Biology
  • Stem Cell Characterization
  • Sulfonephthalein
Mol File:
143-74-8.mol
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Phenol Red Chemical Properties

Melting point:
>300 °C
Boiling point:
>300°C
Density 
1.445 Mg m-3
refractive index 
1.5300 (estimate)
Flash point:
>300°C
storage temp. 
no restrictions.
solubility 
1 M NaOH: soluble1mg/mL
form 
Solid
pka
7.9(at 25℃)
color 
Red
PH Range
6.6(YELLOW)-8.0(RED)
PH
6.8~8.4
Odor
Odorless
Water Solubility 
0.77 g/L
λmax
557nm, 558nm, 360nm, 423nm, 433nm
Merck 
14,7247
BRN 
326470
Major Application
Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity
InChIKey
BELBBZDIHDAJOR-UHFFFAOYSA-N
CAS DataBase Reference
143-74-8(CAS DataBase Reference)
EPA Substance Registry System
Phenol Red (143-74-8)
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Safety Information

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
37/39-26-45-36/37/39-27
WGK Germany 
3
RTECS 
SJ7490000
TSCA 
Yes
HS Code 
29349990
Toxicity
LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71

MSDS

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Phenol Red Usage And Synthesis

Description

Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.

Chemical Properties

dark red powder

Uses

As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red.

Uses

Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method.

Uses

Phenol red solution acts as a pH indicator for the culture medium.

Application

Phenol red solution has been used:
As a tracer dye for microinjection of zebrafish eggs.
As a component of the mMW medium for preparation of mouse embryos.
In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution.

Preparation

Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.

Definition

ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

Safety Profile

Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx.

Enzyme inhibitor

This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination.

Phenol Red Preparation Products And Raw materials

Preparation Products

Raw materials

Phenol RedSupplier

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