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Potassium phthalimide

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Potassium phthalimide Basic information

Product Name:
Potassium phthalimide
Synonyms:
  • 1,3-Dihydroisoindole-1,3-dione potassium salt
  • 1H-Isoindole-1,3(2H)-dione,potassiumsalt
  • n-potassiophthalimide
  • potassiumphthalimidate
  • Nsc167070
  • PotassiumIsoindole-1,3-dione
  • PotassiuM 1,3-dioxoisoindolin-2-ide
  • PHTHALIMIDE POTASSIUM SALT FOR SYNTHESIS
CAS:
1074-82-4
MF:
C8H4KNO2
MW:
185.22
EINECS:
214-046-6
Product Categories:
  • Amination
  • Classes of Metal Compounds
  • K (Potassium) Compounds (excluding simple potassium salts)
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
  • Synthetic Organic Chemistry
  • Typical Metal Compounds
  • Building Blocks
  • Carbonyl Compounds
  • Chemical Synthesis
  • Cyclic Imides
  • Organic Building Blocks
  • Dye
  • pharmaceutical
  • 1074-82-4
Mol File:
1074-82-4.mol
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Potassium phthalimide Chemical Properties

Melting point:
>300°C
Boiling point:
366C
Density 
1.63
storage temp. 
Inert atmosphere,Room Temperature
solubility 
water: soluble50mg/mL, clear to slightly hazy, colorless to yellow
form 
Crystalline Powder
color 
White to yellow or greenish
PH
pH (50g/l, 25℃) : 10.5~12.5
Water Solubility 
Soluble in water.
Sensitive 
Moisture Sensitive
BRN 
3598719
LogP
-1.859
CAS DataBase Reference
1074-82-4(CAS DataBase Reference)
EPA Substance Registry System
Potassium phthalimide (1074-82-4)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-26-60-37
WGK Germany 
3
TSCA 
Yes
HS Code 
29251995
Hazardous Substances Data
1074-82-4(Hazardous Substances Data)

MSDS

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Potassium phthalimide Usage And Synthesis

Chemical Properties

slight yellow-green to white powder

Uses

Potassium Phthalimide is a green, solid-base organocatalys.

Uses

Condensation of phthalimide potassium with organic halide in dimethylformamide has been reported. Reaction of potassium phthalimide and sulfur monochloride in petroleum ether has been studied.

Uses

Potassium phthalimide is usually used as organocatalyst for the cyanosilylation of various carbonyl compounds under extremely mild conditions,and also used as reagent for the transformation of allyl- and alkyl halides into protected primary amines.

Purification Methods

The solid may contain phthalimide and K2CO3 from hydrolysis. If too much hydrolysis has occurred (this can be checked by extraction with cold Me2CO in which the salt is insoluble, evaporate the Me2CO and weigh the residue), it would be better to prepare it afresh. If little hydrolysis has occurred, then recrystallise it from a large volume of EtOH, and wash the solid with a little Me2CO and dry it in a continuous vacuum to constant weight. [Salzerg & Supriawski Org Synth Coll Vol I 119 1941, Raman & IR: Hase J Mol Struct 48 33 1978, Dykman Chem Ind (London) 40 1972, IR, NMR: Assef et al. Bull Soc Chim Fr II 167 1979, Beilstein 21/10 V 270.]

Potassium phthalimideSupplier

Nanjing Dilu Pharmaceutical Co., Ltd Gold
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021-021-50630626 18964684208
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kate@tajilin.com