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Cresol Red

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Cresol Red Basic information

Product Name:
Cresol Red
Synonyms:
  • Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis2-methyl-
  • Cresol Red
  • Cresol Red, Indicator grade, pure 25GR
  • Cresol Red, Indicator grade, pure 5GR
  • Cresol Red (0.1% in ca. 20% Ethanol) [for Titration]
  • 3,3-Bis(3-methyl-4-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide
  • Cresol Red,pure,Indicator grade
  • o-Cresol Red p.a. (green powder)
CAS:
1733-12-6
MF:
C21H18O5S
MW:
382.43
EINECS:
217-064-2
Product Categories:
  • Organics
  • Analytical Chemistry
  • Indicator (pH)
  • pH Indicators
  • Sulfonephthalein
  • bulk reagents
Mol File:
1733-12-6.mol
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Cresol Red Chemical Properties

Melting point:
290 °C
Boiling point:
479.59°C (rough estimate)
Density 
0.998 g/cm3
refractive index 
1.5300 (estimate)
storage temp. 
Store at +5°C to +30°C.
solubility 
Solubility Sparingly soluble in water; soluble in ethanol
form 
Powder
pka
1.0(at 25℃)
color 
Dark green or brown-red
PH Range
7.2(YELLOW)--8.8(PURPLISH RED)
PH
7.2~8.8
Water Solubility 
soluble
λmax
570nm, 367nm, 432nm
Merck 
14,2578
BRN 
343399
Major Application
Display device, optical sensors, combustion gas detection system, inks, correction fluid, diapers, toothpaste, identifying fresh and stale rice, food storage, determine glucose in dialysis solution, monitor metabolic activity of microorganisms, detect bacterialinfection, psychoactive drugs, dental impression material
InChIKey
ASMGMVUGPNODGX-UHFFFAOYSA-N
EPA Substance Registry System
Cresol Red (1733-12-6)
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Safety Information

Hazard Codes 
Xi,Xn,F
Risk Statements 
36/37/38-20/21/22-11
Safety Statements 
24/25-36-26-16
RIDADR 
UN1170 - class 3 - PG 3 - Ethanol, solution
WGK Germany 
3
TSCA 
Yes
HS Code 
29349990
Toxicity
A potent lacrimator which is chemically stable and retains its irritancy in water and so can be used in liquid jets in personnel control. In addition to lacrimation, it causes eye pain, blepharospasm, eyelid swelling, irritation of the conjunctiva, a rise in intraocular pressure, and erythema of the skin. Because it can be used in water, its use is less affected by changes in climatic conditions. It is a more potent lacrimator than CS but it is less potent in lethality than CS.

MSDS

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Cresol Red Usage And Synthesis

Chemical Properties

Dark green or brown-red powder

Uses

Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.

Uses

Acid-base indicator.

Definition

ChEBI: A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups.

Purification Methods

Crystallise it from glacial acetic acid. Dry it in air. Dissolve it in aqueous 5% NaHCO3 solution and precipitate it from a hot solution by dropwise addition of aqueous HCl. Repeat the procedure till the UVmax does not increase. [Beilstein 19 IV 1133.]

Cresol Red Preparation Products And Raw materials

Raw materials

Cresol RedSupplier

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