Basic information Safety Supplier Related

topterone

Basic information Safety Supplier Related

topterone Basic information

Product Name:
topterone
Synonyms:
  • topterone
  • 17β-Hydroxy-17-propylandrost-4-en-3-one
  • Win-17665
  • Androst-4-en-3-one, 17-hydroxy-17-propyl-, (17β)-
CAS:
60607-35-4
MF:
C22H34O2
MW:
330.509
EINECS:
2623214
Mol File:
60607-35-4.mol
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topterone Chemical Properties

Melting point:
114.6-116.0 °C(Solv: benzene (71-43-2); hexane (110-54-3))
Boiling point:
459.8±45.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
pka
15.13±0.60(Predicted)
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topterone Usage And Synthesis

Uses

Topterone functions as steroidal antiandrogen drug. Also, the are used in acne and androgenic alopecia treatment.

in vivo

Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected[1]. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ[2].

topteroneSupplier

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Energy Chemical
Tel
021-58432009 400-005-6266
Email
marketing@energy-chemical.com
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
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topterone(60607-35-4)Related Product Information