Basic information Safety Supplier Related

methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate

Basic information Safety Supplier Related

methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate Basic information

Product Name:
methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate
Synonyms:
  • methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate
  • voacamine
  • 12-Methoxy-13-[(3α)-17-methoxy-17-oxovobasan-3-yl]ibogamine-18-carboxylic acid methyl ester
  • Voacanginine
  • MMH 18
  • NSC 82591
  • Ibogamine-18-carboxylic acid, 12-methoxy-13-[(3α)-17-methoxy-17-oxovobasan-3-yl]-, methyl ester
  • methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate USP/EP/BP
CAS:
3371-85-5
MF:
C43H52N4O5
MW:
704.9
EINECS:
222-151-3
Mol File:
3371-85-5.mol
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methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate Chemical Properties

Melting point:
223℃ (dec.) (methanol )
alpha 
D20 -52° (chloroform)
Density 
1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
form 
A crystalline solid
color 
White to off-white
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methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate Usage And Synthesis

Uses

Voacamine has shown activity against Leishmania ultrastructure through poisoning the bi-subunit topoisomerase IB.

Definition

ChEBI: Voacamine is a citraconoyl group.

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