Basic information Safety Supplier Related

Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI)

Basic information Safety Supplier Related

Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI) Basic information

Product Name:
Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI)
Synonyms:
  • Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI)
  • 5-(t-Butyloxycarbonyl-amino)-3-oxapentanoic acid, [2-(Boc-amino)ethoxy]acetic acid, dicyclohexylamine
  • Boc-O1Pen-OH*DCHA
  • 5-[[(tert-Butoxy)carbonyl]amino]-3-oxapentanoic acid
  • (2-Boc-Aminoethoxy)acetic acid
  • 2-(2-((tert-Butoxycarbonyl)aMino)ethoxy)acetic acid
  • 5-(t-Butyloxycarbonyl-aMino)-3-oxapentanoic acid
  • t-Boc-N-amido-PEG1-CH2CO2H
CAS:
142929-49-5
MF:
C9H17NO5
MW:
219.24
Product Categories:
  • N-BOC
Mol File:
142929-49-5.mol
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Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI) Chemical Properties

Boiling point:
391.2±22.0 °C(Predicted)
Density 
1.151±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.44±0.10(Predicted)
form 
<44.2°C Solid,>67.5°C Liquid
color 
Colorless to light yellow
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Safety Information

HS Code 
9999999999
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Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI) Usage And Synthesis

Description

t-Boc-N-amido-PEG1-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

White crystalline powder

Uses

This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains a single PEG unit to help improve solubility

Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]- (9CI)Supplier

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