3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R] Chemical Properties

storage temp. 

-20°C

form 

liquid

InChI

1S/C26H52NO8P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26(29)32-22-25(35-24(2)28)23-34-36(30,31)33-21-20-27(3,4)5/h25H,6-23H2,1-5H3/t25-/m1/s1

InChIKey

XPAXRSJGGFVTFM-RUZDIDTESA-N

SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COC(CCCCCCCCCCCCCCC)=O)=O

Safety Information

WGK Germany 

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects

Hazard Classifications

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1 Oral
STOT SE 3

3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R] Usage And Synthesis

Uses

1-Palmitoyl-2-acetyl-sn-glycero-3-phosphorylcholine is used in the mRNA combination therapy for treatment of cancer.

Definition

ChEBI: 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine is a 1,2-diacyl-sn-glycero-3-phosphocholine in which the two acyl substituents at positions 1 and 2 are specified as palmitoyl and acetyl respectively. It has a role as a platelet-activating factor receptor agonist. It is functionally related to an acetic acid and a hexadecanoic acid.

Biological Activity

16:0-02:0 PC acts as a receptor (PAF-R) agonist. Increase in the level of phosphocholine (PC) is observed in Alzheimerμs disease.

3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R](79512-78-0)Related Product Information

• 1,2-Distearoyl-sn-glycero-3-phosphocholine
• 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
• 1,2-DI[PERDEUTERO]HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE
• 1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine
• POPC
• 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-CHO LINE MONOHYDRATE
• 1-PALMITOYL-2-(CIS-4,7,10,13,16,19-DOCOSAHEXAENOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE
• 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE DIHYDRATE
• PHOSPHATIDYLCHOLINE, L-ALPHA-DIPALMITOYL, [CHOLINE-METHYL-14C]
• 1-HEXADECANOYL-2-(1-PYRENEHEXANOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE
• 2-(6-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)HEXANOYL-1-HEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE