Basic information Safety Supplier Related

1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE

Basic information Safety Supplier Related

1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE Basic information

Product Name:
1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE
Synonyms:
  • BETA-PY-C10-HPC
  • L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-(PYREN-1-YL)DECANOYL-GAMMA-PALMITOYL
  • 10-PYRENE-PC
  • 1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE
  • 1-O-HEXADECANOYL-2-O-(10-(1-PYRENYL)DECANOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 1-HEXADECANOYL-2-(1-PYRENEDECANOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE
  • (7R)-4-hydroxy-N,N,N-triMethyl-10-oxo-7-[[1-oxo-10-(1-pyrenyl)decyl]oxy]-3,5,9-Trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide
  • 3-PalMitoyl-2-(1-pyrenodecanoyl)-L-α-phosphatidylcholine
CAS:
95864-17-8
MF:
C50H76NO8P
MW:
850.13
Product Categories:
  • Aromatics
  • Fatty Acid Derivatives & Lipids
  • Fluorescent Labels & Indicators
  • Glycerols
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
95864-17-8.mol
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1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE Chemical Properties

storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
powder
Appearance
Solid Powder
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Safety Information

WGK Germany 
3

MSDS

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1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE Usage And Synthesis

Description

10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.

Uses

1-Palmitoyl-2-pyrenedecanoylphosphatidylcholine is a fluorescent phospholipid used to study the mechanism of spontaneous phospholipid transfer between single-walled phospholipid vesicles (liposomes) and other membrane interactions.

References

[1] ROBERTS M F. Phospholipases: structural and functional motifs for working at an interface[J]. FASEB Journal, 1996, 10 10: 1159-1172. DOI: 10.1096/fasebj.10.10.8751718
[2] S LUSA. Degradation of pyrene-labelled phospholipids by lysosomal phospholipases in vitro. Dependence of degradation on the length and position of the labelled and unlabelled acyl chains.[J]. Biochemical Journal, 1996, 315 ( Pt 3): 947-952. DOI: 10.1042/bj3150947

Excitation / Emission Maximum

342 nm/376 nm

1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINESupplier

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1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE(95864-17-8)Related Product Information