1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE CAS#: 20559-16-4

1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Basic information

Product Name:

1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Synonyms:

L-GAMMA-MYRISTOYL-ALPHA-LYSOLECITHIN
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, MYRISTOYL
LYSOLECITHIN, MYRISTOYL
1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE
1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3-SN-LYSOPHOSPHATIDYLCHOLINE, 1-MYRISTOYL
14:0 LYSO PC

CAS:

20559-16-4

MF:

C22H46NO7P

MW:

467.58

Mol File:

20559-16-4.mol

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1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties

Melting point:: >142°C (dec.)
storage temp.: −20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
InChI: InChI=1/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3/t21-/s3
InChIKey: VXUOFDJKYGDUJI-DLINEHSKNA-N
SMILES: P([O-])(=O)(OCC[N+](C)(C)C)OC[C@H](O)COC(=O)CCCCCCCCCCCCC |&1:12,r|

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Safety Information

WGK Germany: 3
F: 10

MSDS

Language:English Provider:SigmaAldrich

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1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Usage And Synthesis

Description

1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is a lysophospholipid (LyP), which is a monoglycerophospholipid in which the phosphorylcholine moiety occupies the glycerol substitution site. LysoPC(14:0/0:0) has a potent antispasmodic effect.

Physical properties

1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is a Solid,it can insoluble in water.

Uses

1-Myristoyl-sn-glycero-3-phosphocholine is a derivative of sn-Glycero-3-phosphocholine (G598700) and can be used as a biomarker in biological studies.

Definition

ChEBI: 1-myristoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 14:0 in which the acyl group specified is myristoyl. The major species at pH 7.3. It is a lysophosphatidylcholine 14:0, a 1-O-acyl-sn-glycero-3-phosphocholine and a tetradecanoate ester.

in vivo

Of the saturated fatty acid-containing L-α-lysolecithins (LPC), palmitoyl-LPC shows the strongest antispasmodic effect against acetylcholine- or histamine-induced guinea pig ileum contraction; the order of potency of the others is (LysoPC(14:0/0:0)) myristoyl- > stearoyl-, lauroyl- > decanoyl-LPC. Incorporation of a cis-double bond into the C18 fatty acid chain of LPC resulted in a slight decrease of the antispasmodic effect^[1].

IC 50

Human Endogenous Metabolite

1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINESupplier

AVT(Shanghai) Pharmaceutical Tech Co., Ltd. Gold

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Shanghai T&W Pharmaceutical Co., Ltd.

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Email: anhua.mao@aladdin-e.com

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