L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, LAUROYL Chemical Properties

storage temp. 

−20°C

form 

powder

InChI

1S/C20H42NO7P/c1-5-6-7-8-9-10-11-12-13-14-20(23)26-17-19(22)18-28-29(24,25)27-16-15-21(2,3)4/h19,22H,5-18H2,1-4H3/t19-/m1/s1

InChIKey

BWKILASWCLJPBO-LJQANCHMSA-N

Safety Information

WGK Germany 

3

Storage Class

6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects

Hazard Classifications

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, LAUROYL Usage And Synthesis

Uses

12:0 Lyso PC may be used to reversibly block envelope glycoprotein (Env)-mediated fusion in various cell lines. It may also be used in determining bubble local velocity profile.

Definition

ChEBI: A 1-O-acyl-sn-glycero-3-phosphocholine in which the acyl group is specified as lauroyl (dodecanoyl)

Biological Activity

Lysophosphatidylcholine (LPC) alters various functions in different cell-types, like endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. It is associated with atherosclerosis and inflammatory diseases. LPC activates many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases.

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