3-Bromo-2-fluoroaniline Chemical Properties

Boiling point:

228℃

Density 

1.694

Flash point:

91℃

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

pka

2.13±0.10(Predicted)

form 

liquid

color 

Clear, light yellow

InChI

InChI=1S/C6H5BrFN/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2

InChIKey

HYPQOSVTIONWSN-UHFFFAOYSA-N

SMILES

C1(N)=CC=CC(Br)=C1F

Safety Information

Safety Statements 

24/25

HS Code 

29214300

3-Bromo-2-fluoroaniline Usage And Synthesis

Description

3-Bromo-2-fluoroaniline is an aniline derivative with reactive groups (fluorine and bromine atoms). It is widely used in organic synthesis and can be used as a starting material for the synthesis of KRASG12C inhibitors, which have antitumour activity and can be used in the development of anticancer drugs.

Uses

3-Bromo-2-fluoroaniline is used in the preparation of heterotricyclic carboxamides as RIG-1 agonists for treatment cell proliferation disorders.

3-Bromo-2-fluoroaniline(58534-95-5)Related Product Information

• 4'-Bromoacetanilide
• 2-Bromoaniline
• 2,4,6-Tribromoaniline
• 2-Bromo-5-fluorobenzyl alcohol
• 2-(Trifluoromethoxy)benzyl bromide
• 2-BROMO-4-FLUOROBENZYL ALCOHOL
• 3-Bromo-2-fluoro-phenol
• Methyl 2-amino-4-bromobenzoate
• 2-Bromo-5-fluorobenzyl bromide
• (3-bromo-2-fluorophenyl)methanol
• 4-Bromo-2-chlorobenzoic acid
• 3-Bromo-5-nitrobenzoic acid
• 4-BROMO-3-CHLOROBENZOIC ACID
• 4-Bromo-2-nitrobenzoic acid
• 5-AMINO-2-BROMOBENZOIC ACID
• 3,5-DIBROMO-2-METHOXYBENZOIC ACID