Basic information Safety Supplier Related

2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)-

Basic information Safety Supplier Related

2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)- Basic information

Product Name:
2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)-
Synonyms:
  • 2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)-
  • α-Glucosidase-IN-4
  • 2-Oxo-2H-chromen-4-yl (E)-3-(p-tolyl)acrylate
CAS:
2410538-67-7
MF:
C19H14O4
MW:
306.32
Mol File:
2410538-67-7.mol
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2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)- Chemical Properties

Boiling point:
510.4±49.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
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2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)- Usage And Synthesis

Uses

α-Glucosidase-IN-4 is a reversible and mixed type α-glucosidase inhibitor with an IC50 of 12.98 μM, a KI of 27.02 μM, and a KIS of 13.65 μM, respectively[1].

References

[1] Xu XT, et al. Synthesis and biological evaluation of coumarin derivatives as α-glucosidase inhibitors. Eur J Med Chem. 2020;189:112013. DOI:10.1016/j.ejmech.2019.112013

2-Propenoic acid, 3-(4-methylphenyl)-, 2-oxo-2H-1-benzopyran-4-yl ester, (2E)-Supplier

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