Basic information Safety Supplier Related

Oxypendyl

Basic information Safety Supplier Related

Oxypendyl Basic information

Product Name:
Oxypendyl
Synonyms:
  • Oxypendyl
  • 4-[3-(10H-Pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-1-piperazineethanol
  • Oxipendyl
  • 2-[4-(3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropyl)piperazin-1-yl]ethanol
  • 1-Piperazineethanol, 4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-
CAS:
5585-93-3
MF:
C20H26N4OS
MW:
370.51
Mol File:
5585-93-3.mol
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Oxypendyl Chemical Properties

Boiling point:
bp1 260-265°; bp6 280-300°
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Oxypendyl Usage And Synthesis

Originator

Pervetral, Homburg , W. Germany ,1962

Definition

ChEBI: Oxypendyl is a tertiary amino compound and an aromatic amine.

Manufacturing Process

32 parts of 10-(γ-N-piperazinopropyl)-4-azaphenthiazine in 200 cc of butanol with 9 parts of ethylene chlorohydrin and 14 parts of finely powdered potash are heated for 4 hours under reflux while stirring vigorously. After cooling, extraction is carried out with dilute hydrochloric acid, the substance is finally washed with water and the combined hydrochloric acid aqueous phase is washed twice with ether. The base is then liberated with concentrated sodium hydroxide solution and taken up in chloroform. The chloroform solution is dried with potash and concentrated by evaporation. 26.4 parts of (10-γ-N-Bhydroxyethylpiperazino-N1-propyl)-4-azaphenthiazine are distilled over at 280°C to 300°C/6 mm. The dihydrochloride is obtained in isopropanol with isopropanolic hydrochloric acid. The product melts at 218°C to 220°C.

Therapeutic Function

Antiemetic

OxypendylSupplier

Lanospharma Laboratories Co.,Ltd
Tel
13440048448
Email
sales@lanospharma.com
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Oxypendyl(5585-93-3)Related Product Information