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BERBAMINE DIHYDROCHLORIDE

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BERBAMINE DIHYDROCHLORIDE Basic information

Product Name:
BERBAMINE DIHYDROCHLORIDE
Synonyms:
  • BERBENINE
  • BERBAMINE DIHYDROCHLORIDE
  • BERBAMINE HCL
  • BERBAMINE 2HCL
  • (4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-21,22,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-12-ol hydrochloride
  • 6,6',7-Trimethoxy-2,2'-dimethylberbaman-12-ol dihydrochloride
  • Berbaman-12-ol,6,6',7-trimethoxy-2,2'-dimethyl-, dihydrochloride (9CI)
  • Berbamine dihydrochloride, >95%
CAS:
6078-17-7
MF:
C37H42Cl2N2O5
MW:
665.65
EINECS:
200-001-8
Product Categories:
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • Inhibitors
Mol File:
6078-17-7.mol
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BERBAMINE DIHYDROCHLORIDE Chemical Properties

Melting point:
250-253 °C(lit.)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
≥68 mg/mL in DMSO; ≥10.68 mg/mL in H2O; ≥4.57 mg/mL in EtOH
form 
solid
optical activity
[α]20/D +116°, c = 1% in ethanol
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3

MSDS

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BERBAMINE DIHYDROCHLORIDE Usage And Synthesis

Uses

Reactant for:

  • Preparation of and anti-leukemia active berbamine derivatives

Uses

(+)-Berbamine Dihydrochloride exerts anti-inflammatory effects through inhibition of NF-κB and MAPK signalling pathways.

Biological Activity

extracted from berberidis;store the product in sealed, cool and dry condition

target

cAMP | Calcium Channel

BERBAMINE DIHYDROCHLORIDESupplier

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