bruceoside A
bruceoside A Basic information
- Product Name:
- bruceoside A
- Synonyms:
-
- 13,20-Epoxy-2-(β-D-glucopyranosyloxy)-11β,12α-dihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-3,16-dioxopicras-1-en-21-oic acid methyl ester
- (11beta,12alpha,15beta)-13,20-Epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-picras-1-en-21-oic acid methyl ester
- bruceoside A
- Picras-1-en-21-oic acid, 13,20-epoxy-2-(β-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-, methyl ester, (11β,12α,15β)-
- Bruceside A
- CAS:
- 63306-30-9
- MF:
- C32H42O16
- MW:
- 682.67
- Mol File:
- 63306-30-9.mol
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bruceoside A Chemical Properties
- Melting point:
- 184-189 °C
- Boiling point:
- 895.2±65.0 °C(Predicted)
- Density
- 1.55±0.1 g/cm3(Predicted)
- pka
- 12.42±0.70(Predicted)
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bruceoside A Usage And Synthesis
Uses
Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity[1].
Definition
ChEBI: Bruceoside A is a triterpenoid saponin.
in vivo
Bruceoside A could be transformed into the potent anticancer component brusatol in vivo, rather than its direct deglycosylated metabolite bruceosin[1].
| Animal Model: | Male ICR mice weighing 25.0 ± 5.0 g[1]. |
| Dosage: | 22.5 mg/kg. |
| Administration: | Intragastrically administrated. |
| Result: | Reached its highest levels in three hours with a half-life value of 3.99 h. |
References
[1] Yuan Xu, et al. Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae. J Pharm Biomed Anal. 2019 Jun 5;170:264-272. DOI:10.1016/j.jpba.2019.03.052
bruceoside ASupplier
Wuhan ChemFaces Biochemical Co., Ltd.
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- 021-65675885 18964387627
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Shandong Xiya Chemical Co., Ltd.
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Chengdu Push Bio-Technology Co., Ltd.
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- 028-028-85370565-229-229 18080489829
- 18080489829@163.com
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bruceoside A(63306-30-9)Related Product Information
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- bruceoside A
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