Mono-POC Tenofovir Chemical Properties

Melting point:

303-305°C (dec.)

Boiling point:

599.3±60.0 °C(Predicted)

Density 

1.56±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Dichloromethane (Slightly), Methanol (Slightly, Heated), Water (Slightly)

form 

Solid

pka

1.88±0.10(Predicted)

color 

White to Light Beige

Stability:

Hygroscopic

InChI

InChI=1S/C14H22N5O7P/c1-9(2)26-14(20)23-7-25-27(21,22)8-24-10(3)4-19-6-18-11-12(15)16-5-17-13(11)19/h5-6,9-10H,4,7-8H2,1-3H3,(H,21,22)(H2,15,16,17)/t10-/m1/s1

InChIKey

XLYSRKLPLHUWCJ-SNVBAGLBSA-N

SMILES

C(OC(C)C)(=O)OCOP(=O)(O)CO[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2

Mono-POC Tenofovir Usage And Synthesis

Chemical Properties

White Solid

Uses

An impurity of Tenofovir Disoproxil (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. It is used as an anti-HIV agent and an antiviral.

Uses

An impurity of Tenofovir disoproxil (T018505).

Mono-POC Tenofovir(211364-69-1)Related Product Information

• 6N-HydroxyMethyl Tenofovir Disoproxil
• D-Alanine Isopropyl Ester HCl
• Mono-POC Isopropyl Tenofovir
• Tenofovir Disoproxil Related Compound B (10 mg) ((E)-9-(Prop-1-enyl)-9H-purin-6-amine)
• nPOC-POC Tenofovir (Mixture of DiastereoMers)
• Tenofovirdisoproxil Impurity
• Mono-POC Methyl Tenofovir (Mixture of DiastereoMers)
• Mono-POC Isopropyl Tenofovir (Mixture of DiastereoMers)
• Diethyl-carbaMic Acid ChloroMethyl Ester
• Tenofovir Impurity 95
• (R)-(((1-(6-amino-3H-purin-3-yl)propan-2-yl)oxy)methyl)phosphonic acid
• Tenofovir Disopropyl Ethyl Diester
• Tenofovir
• 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox
• (S)-Tenofovir
• ChloroMethyl Propyl Carbonate
• Chloromethyl isopropyl carbonate
• rac-Tenofovir-d7