Basic information Safety Supplier Related

Irinotecan Lactone IMpurity

Basic information Safety Supplier Related

Irinotecan Lactone IMpurity Basic information

Product Name:
Irinotecan Lactone IMpurity
Synonyms:
  • Irinotecan Lactone IMpurity
  • Irinotecan Impurity 20
  • [1,4'-Bipiperidine]-1'-carboxylic Acid 3,10-Diethyl-11,13-dihydro-1,13-dioxo-1H,3H- furo[3',4':6,7]indolizino[1,2-b]quinolin-8-yl Ester
  • Irinotecan quinone lactone impurity
  • 3,10-diethyl-1,13-dioxo
  • 3,10-diethyl-1,13-dioxo-1,3,11,13-tetrahydrofuro[3',4':6,7]indolizino[1,2-b]quinolin-8-yl [1,4'-bipiperidine]-1'-carboxylate? (Irinotecan Impurity)
  • 3,10-diethyl-1,13-dioxo-1,3,11,13-tetrahydrofuro[3',4':6,7]indolizino[1,2-b]quinolin-8-yl [1,4'-bipiperidine]-1'-carboxylate (Irinotecan Impurity)
CAS:
143490-53-3
MF:
C32H36N4O5
MW:
556.65
Product Categories:
  • Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
143490-53-3.mol
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Irinotecan Lactone IMpurity Chemical Properties

Melting point:
>90°C (dec.)
Boiling point:
843.9±65.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly, Heated, Sonicated)
pka
9.33±0.20(Predicted)
form 
Solid
color 
Pale Yellow to Light Yellow
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Irinotecan Lactone IMpurity Usage And Synthesis

Uses

A lactone impurity of Irinotecan (I767500), a DNA topoisomerase inhibitor. A photodegradation product of a camptothecin derivative used as an anticancer drug.

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