3-Ethoxy-4-methoxybenzaldehyde Chemical Properties

Melting point:

51 °C

Boiling point:

155°C/10mmHg(lit.)

Density 

1.088±0.06 g/cm3(Predicted)

Flash point:

113 °C

storage temp. 

room temp

solubility 

Soluble in methanol.

form 

powder to crystal

color 

White to Orange to Green

Sensitive 

Air Sensitive

InChIKey

VAMZHXWLGRQSJS-UHFFFAOYSA-N

CAS DataBase Reference

1131-52-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Safety Statements 

23-24/25

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29124990

MSDS

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3-Ethoxy-4-methoxybenzaldehyde Usage And Synthesis

Chemical Properties

Colorless solid

Uses

3-Ethoxy-4-methoxybenzaldehyde is used as a pharmaceutical intermediate.

Application

3-Ethoxy-4-methoxybenzaldehyde may be used to synthesize Compound of Designation red 10 binding (CDr10b) to investigate its role in neuroinflammatory diseases.

Synthesis

In a 3 L dry reaction flask, 157 g of sodium hydroxide was dissolved in 1500 ml of water, 500 g of isovanillin, 120 g of tetrabutylammonium fluoride, and 537 g of ethyl bromide were added, and the reaction was stirred at 25°C for 4 hours. After filtration by suction, an off-white solid powder of 3-ethoxy-4-methoxybenzaldehyde was obtained with a purity of 99.9% and a yield of 96.1%.

General Description

3-Ethoxy-4-methoxybenzaldehyde is a derivative of vanillin.

3-Ethoxy-4-methoxybenzaldehyde(1131-52-8)Related Product Information

• Benzaldehyde
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• o-Anisaldehyde
• 4-Hydroxybenzaldehyde
• 2-Ethoxybenzaldehyde
• 2,6-Dimethoxybenzaldehyde
• Anisole
• (Trifluoromethoxy)benzene
• p-Anisaldehyde
• 3-BENZYLOXY-4-METHOXYBENZOIC ACID
• 3,4-Dibenzyloxybenzaldehyde
• 2,4,5-TRIETHOXYBENZOPHENONE
• 4',4''(5'')-DIACETYLDIBENZO-18-CROWN-6
• 3,4-DIETHOXYBENZALDEHYDE
• 3-Benzyloxy-4-methoxybenzaldehyde
• 3,4-Diethoxybenzoic acid
• 3,4,5-TRIETHOXYBENZOIC ACID
• 3,4-DIACETOXY-BENZOIC ACID