1-O-ALPHA-D-GLUCOPYRANOSYL-D-MANNITOL Chemical Properties

Melting point:

162°C

alpha 

[α]D20 +88～+94°(c=4,dil.NH4OH)

Boiling point:

788.5±60.0 °C(Predicted)

Density 

1.69±0.1 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

pka

12.89±0.70(Predicted)

color 

White to Off-White

Stability:

Hygroscopic

EPA Substance Registry System

D-Mannitol, 1-O-.alpha.-D-glucopyranosyl- (20942-99-8)

Safety Information

TSCA 

TSCA listed

1-O-ALPHA-D-GLUCOPYRANOSYL-D-MANNITOL Usage And Synthesis

Uses

1-O-a-D-Glucopyranosyl-D-mannitol is used in the nutritional and biochemical investigations on disaccharide alcohols.

Definition

ChEBI: Isomalt is a diastereoisomeric mixture composed of 1-O-alpha-D-glucopyranosyl-D-mannitol dihydrate and 6-O-alpha-D-glucopyranosyl-D-glucitol in a 1:1 ratio. It is used in the food industry as a sugar substitute and in the pharmaceutical industry as a tabletting excipient. It has a role as a sweetening agent, an excipient and a plasticiser. It contains a 6-O-alpha-D-glucopyranosyl-D-glucitol and a 1-O-alpha-D-glucopyranosyl-D-mannitol dihydrate.

Synthesis

The synthesis of 1-O--D-glucopyranosyl-D-mannitol dihydrate (hereinafter referred to as 1,1-GPM) is generally a two-step process: 1) the enzymatic conversion of sucrose to isomaltosucrose in the first place, and 2) the subsequent hydrogenation of the isolated isomaltosucrose over a Raney nickel catalyst. Where the conversion of sucrose to isomaltosucrose can be accomplished by the microorganism Prochlorococcus erythropolis, the isomaltosucrose obtained in this manner is converted by hydrogenation in the presence of a Raney nickel catalyst to a mixture of 1,1-GPM and 6-O--D-glucopyranosyl-D-sorbitanol (abbreviated to 1,6-GPS), which is then concentrated by a process of evaporation and cooling crystallization.

1-O-ALPHA-D-GLUCOPYRANOSYL-D-MANNITOL(20942-99-8)Related Product Information

• 1-O-ALPHA-D-GLUCOPYRANOSYL-D-MANNITOL
• Isomalt
• MAN1-A-6[MAN1-A-3][MAN1-A-4]MAN-BETA-O-PNP