5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Basic information
- Product Name:
- 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- Synonyms:
-
- 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- AN-2718
- 5-Chloro-1,3-dihydro-2,1-benzoxaborol-1-ol, 95%
- 5-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
- 5-Chloro-2,1-benzoxaborol-1(3H)-ol
- 2,1-Benzoxaborole, 5-chloro-1,3-dihydro-1-hydroxy-
- Inhibitor,AN2718,AN 2718,Fungal,AN-2718,inhibit
- CAS:
- 174672-06-1
- MF:
- C7H6BClO2
- MW:
- 168.39
- Product Categories:
-
- API
- Mol File:
- 174672-06-1.mol
More
Less
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Chemical Properties
- Melting point:
- 150-154 °C
- Boiling point:
- 273.2±50.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL
- form
- A crystalline solid
- pka
- 6.60±0.20(Predicted)
More
Less
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole Usage And Synthesis
Biological Activity
AN-2718 inhibits the growth of fungi by inhibiting protein synthesis through the OBORT mechanism.
in vitro
AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus , and from yeasts, C. albicans , with an IC 50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T. mentagrophytes .
target
Fungal.
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaboroleSupplier
Shijiazhuang Leather Bureau Chemical Technology Co., Ltd. Gold
- Tel
- 13020863400
- liaoy124@163.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Changzhou Renaissance Chem Co. Ltd
- Tel
- 86-519-86202821
Shanghai Balmxy Pharmaceutical Co., Ltd
- Tel
- 021-24206007 13764915196
- sales@balmxy.com
ShangHai AmK Pharmaceutical Technology Co., Ltd.
- Tel
- 18019252918
- sale@amkchem.com
More
Less
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole(174672-06-1)Related Product Information
- Isopropylmagnesium chloride lithium chloride complex
- 1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-7-carboxylic acid
- 6-(hydroxymethyl)benzo[c][1,2]oxaborol-1(3H)-ol
- 2,1-Benzoxaborole,1,3-dihydro-1-hydroxy-6-Methoxy
- 6-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
- 1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-5-carbonitrile