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ARS-853

Basic information Safety Supplier Related

ARS-853 Basic information

Product Name:
ARS-853
Synonyms:
  • ARS-853
  • ARS-853 (ARS853)
  • CS-2646
  • 2-Propen-1-one, 1-[3-[4-[2-[[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl]amino]acetyl]-1-piperazinyl]-1-azetidinyl]-
  • 1-(3-(4-((4-chloro-2-hydroxy-5-(1-methylcyclopropyl)phenyl)glycyl)piperazin-1-yl)azetidin-1-yl)prop-2-en-1-one
  • ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,covalent,ARS853,G12C
  • ARS-853, 10 mM in DMSO
CAS:
1629268-00-3
MF:
C22H29ClN4O3
MW:
432.94
Mol File:
1629268-00-3.mol
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ARS-853 Chemical Properties

Boiling point:
691.6±55.0 °C(Predicted)
Density 
1.357±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 50 mg/ml
form 
A crystalline solid
pka
9.47±0.50(Predicted)
color 
White to off-white
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ARS-853 Usage And Synthesis

Uses

ARS-853 is an allele-specific inhibitor that inhibits KRASG12C signaling and cancer cell growth.

IC 50

KRAS(G12C): 2.5 μM (IC50)

ARS-853Supplier

BOC Sciences
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Dalian Meilun Biotech Co., Ltd.
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MedChemexpress LLC
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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