2-Benzylpropionic acid Chemical Properties

Melting point:

39-41 °C(lit.)

Boiling point:

167-168 °C23 mm Hg(lit.)

Density 

1.065 g/mL at 25 °C(lit.)

refractive index 

1.5155 (estimate)

Flash point:

>230 °F

pka

4.69±0.10(Predicted)

form 

Crystalline Powder or Crystals

color 

White to light yellow

InChI

InChI=1S/C10H12O2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,11,12)

InChIKey

MCIIDRLDHRQKPH-UHFFFAOYSA-N

SMILES

C1(=CC=CC=C1)CC(C)C(=O)O

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29163900

MSDS

• Language:English Provider:2-Benzylpropionic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-Benzylpropionic acid Usage And Synthesis

Chemical Properties

white to light yellow crystalline powder or

Uses

α-Methylhydrocinnamic acid is suitable for use in the comparative study to investigate the γ-globin inducibility of short-chain fatty acid derivatives (SCFADs) in mice. It may be used as a histone deacetylase (HDAC) inhibitor in the comparative study to investigate the EGFP-induction potency of a number of HDAC inhibitors. It may be used in the study to investigate the selectivity of the sensor based on imprinted poly(o-phenylenediamine) (iPoPD).

General Description

α-Methylhydrocinnamic acid (2-methyl-3-phenylpropionic acid, 2-benzylpropionic acid) is a cinnamic acid derivative. Its synthesis by the asymmetric hydrogenation of α-methylcinnamic acid has been reported. α-Methylhydrocinnamic acid, a short chain fatty acid derivative (SCFAD), has been reported to correct the cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR) defect. Conformational studies of 2-methyl-3-phenylpropionic acid has been investigated by NMR spectroscopy. The enantiomers of 2-benzylpropionic acid has been reported to be synthesized using a lipase-catalyzed resolution. (S) (+)-2-methyl-3-phenylpropionic acid participates in the synthesis of optically active (R)-5-methyl-6-phenylhexanoyl azide. L-2-Methyl-3.phenylpropionic acid has been reported to be an inhibitor of carboxypeptidase A. Polymer-supported “Evans” oxazolidinone mediated solid phase asymmetric has been employed in the synthesis of (S)-2-methyl-3-phenylpropionic acid.

2-Benzylpropionic acid(1009-67-2)Related Product Information

• N,N-Dimethylbenzylamine
• Benzyltriethylammonium chloride
• α-Lipoic Acid
• Cinnamyl cinnamate
• Benzyltrimethylammonium chloride
• DIBENZYLTOLUENE
• Citric acid
• Folic acid
• Hyaluronic acid
• Methyl cinnamate
• 2-Chloropropionic acid
• 2,3-Dibromopropionic acid
• Cinnamic acid
• 3-(Trifluoromethyl)cinnamic acid
• Octyl 4-methoxycinnamate
• Ethyl cinnamate
• 2,2-Bis(hydroxymethyl)propionic acid
• Ethyl 2-(Chlorosulfonyl)acetate