AC2-12
AC2-12 Basic information
- Product Name:
- AC2-12
- Synonyms:
-
- Annexin A1 (1-11) (dephosphorylated) (huMan, bovine, chicken, porcine) Annexin-1 (2-12) (huMan, bovine, chicken, porcine), Lipocortin-1 (2-12), Calpactin II (1-11) (dephosphorylated) (huMan, bovine, chicken, porcine)
- Annexin-1 (2-12) (huMan, bovine, chicken, porcine), Lipocortin-1 (2-12), Calpactin II (1-11) (dephosphorylated) (huMan, bovine, chicken, porcine)
- Annexin A1
- ANTI-ANNEXIN A1 (CENTER) antibody produced in rabbit
- ANX1
- LPC1
- Annexin 1 (ANXA - 1
- Annexin A1 (1-11) (dephosphorylated)
- CAS:
- 256447-08-2
- MF:
- C63H94N14O17S
- MW:
- 1351.57
- Product Categories:
-
- peptide
- Mol File:
- 256447-08-2.mol
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AC2-12 Chemical Properties
- storage temp.
- -20°C
- Water Solubility
- Soluble to 1 mg/ml in 20% acetonitrile / Water
- Sequence
- Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-OH
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AC2-12 Usage And Synthesis
Enzyme inhibitor
This annexin/lipocortin-1 peptidomimetic (FW = 1351.58 g/mol; Sequence: Acetyl-AMVSEFLKQAW; CAS 256447-08-2; Soluble to 1 mg/mL in 20% (vol/vol) acetonitrile-H2O) markedly reduces the degree of neutrophil adhesion and emigration across mouse mesenteric postcapillary venules, when administered at 13 mg/kg (s.c.), but does not modify cell rolling, when assessed directly by intravital microscopy. Ac2-12 also promotes neutrophil detachment from mesenteric endothelium after activation by intraperitoneal injection of 1 mg zymosan in mice (i.e., zymosan peritonitis). Ac2-12 phenocopies the effects observed in FormylatedPeptide Receptor (FPR) knock-out mice.
AC2-12Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-021-64543801 13764082696
- 2355241799@qq.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
Cellmano Biotech Limited
- Tel
- 0551-65326643 18156095617
- info@cellmano.com
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AC2-12(256447-08-2)Related Product Information
- H-LYS-SER-ASP-GLY-GLY-VAL-LYS-LYS-ARG-LYS-SER-SER-SER-SER-OH
- ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU
- H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH
- CALP2
- CALMODULIN-DEPENDENT PROTEIN KINASE II (281-309)
- ITSFEEAKGLDRINERMPPRRDAMP
- ANGIOGENIN (108-122)
- AC2-26
- AC2-12