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HEPTAMINOL HYDROCHLORIDE

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HEPTAMINOL HYDROCHLORIDE Basic information

Product Name:
HEPTAMINOL HYDROCHLORIDE
Synonyms:
  • (5-Hydroxy-1,5-diMethylhexyl)aMine Hydrochloride
  • 2-AMino-6-hydroxy-6-Methylheptane Hydrochloride
  • 6-Hydroxy-6-Methyl-2-aMinoheptane Hydrochloride
  • 6-Hydroxy-6-Methyl-2-heptaMine Hydrochloride
  • 6-Hydroxy-6-Methyl-2-heptylaMine Hydrochloride
  • Corasore Hydrochloride
  • 2-methyl-6-amino-2-heptanolhydrochloride
  • 6-amino-2-methyl-2-heptanohydrochloride
CAS:
543-15-7
MF:
C8H20ClNO
MW:
181.7
EINECS:
208-837-5
Product Categories:
  • Aliphatics
  • Amines
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
Mol File:
543-15-7.mol
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HEPTAMINOL HYDROCHLORIDE Chemical Properties

Melting point:
165-167 °C(lit.)
storage temp. 
Store at -20°C
solubility 
Freely soluble in water, soluble in alcohol, practically insoluble in methylene chloride.
form 
Solid
color 
White to off-white
Sensitive 
Hygroscopic
Merck 
14,4657
BRN 
3673011
CAS DataBase Reference
543-15-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
MJ3240000
Toxicity
LD50 intraperitoneal in mouse: 900mg/kg

MSDS

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HEPTAMINOL HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White or almost white, crystalline powder

Uses

Antihypotensive

Uses

Heptaminol Hydrochloride is used in the preparation of drugs for treating cardiovascular and cerebrovascular diseases.

in vivo

Heptaminol hydrochloride (12 μL; 50% water/acetone) stimulates NO synthesis from constitutive NOS and attenuates TPA-induced depletion of NK cells at the edge of the mouse ear. Heptaminol hydrochloride exerts anti-proliferative and anti-inflammatory effects on TPA, suggesting important anti-tumor function[2].

Animal Model:Acute TPA-induced inflammatory ear skin changes in Balb/c mouse (5-7 wk)[2]
Dosage:2.5 nmol Heptaminol in 12 μL
Administration:Topical treatment for single dose; Heptaminol was dissolved in 50% water/acetone; 30 min before 0.4 nmol TPA (in 12 μL acetone) treatment.
Result:Stimulated NO production and directly inhibits tumors caused by TPA promoting inflammation.

HEPTAMINOL HYDROCHLORIDESupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Email
market03@meryer.com
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Email
sales@chem-strong.com
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