Basic information Safety Supplier Related

dactylocycline A

Basic information Safety Supplier Related

dactylocycline A Basic information

Product Name:
dactylocycline A
Synonyms:
  • dactylocycline A
  • 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-6-[[2,3,6-trideoxy-3-(hydroxyamino)-3-C-methyl-4-O-methyl-α-L-arabino-hexopyranosyl]oxy]-, [4R-(4α,4aα,5aα,6α,12aα)]- (9CI)
  • Dactylocycline
CAS:
125622-12-0
MF:
C31H40ClN3O13
MW:
698.11
Mol File:
125622-12-0.mol
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dactylocycline A Chemical Properties

Boiling point:
943.0±75.0 °C(Predicted)
Density 
1.59±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)
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dactylocycline A Usage And Synthesis

Description

Dactylocyclines is novel tetracycline derivatives produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp. (ATCC 53693), a producer of several novel tetracycline derivatives. The major fermentation products, dactylocyclines A and B, were purified and MIC values determined against tetracycline-resistant and tetracycline-sensitive Gram-positive bacteria. The dactylocyclines represent the first naturally occurring tetracycline C2 amides which lack cross resistance with tetracycline.

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