OXONIC ACID POTASSIUM SALT
OXONIC ACID POTASSIUM SALT Basic information
- Product Name:
- OXONIC ACID POTASSIUM SALT
- Synonyms:
-
- 1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt
- 5-azaoroticacid,potassiumsalt
- 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt, Allantoxanic acid
- （OXO）Oteracil potassium
- Potassium 4,6-dioxo-1H-1,3,5-triazine-2-carboxylate
- Potassium s-triazine-2,4-dione-6-carboxylate
- 1,4,5,6-Tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid potassium salt
- Allantoxanic acid potassium
- CAS:
- 2207-75-2
- MF:
- C4H2KN3O4
- MW:
- 195.17
- EINECS:
- 218-627-5
- Product Categories:
-
- Anti-cancer&immunity
- oncology
- Classes of Metal Compounds
- K (Potassium) Compounds (excluding simple potassium salts)
- Typical Metal Compounds
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Anticancer
- Mol File:
- 2207-75-2.mol
OXONIC ACID POTASSIUM SALT Chemical Properties
- Melting point:
- 300 °C(lit.)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
- form
- Powder
- color
- White
- Water Solubility
- Soluble in hot water.
- CAS DataBase Reference
- 2207-75-2(CAS DataBase Reference)
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- RR4580000
- HS Code
- 29349990
MSDS
- Language:English Provider:4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
OXONIC ACID POTASSIUM SALT Usage And Synthesis
Description
Oxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; ), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats. Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas.
Chemical Properties
Off-White Solid
Uses
Antitumor effect potentiator and antitumor agent
Uses
Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.
Definition
ChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity.
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OXONIC ACID POTASSIUM SALT(2207-75-2)Related Product Information
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