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OXONIC ACID POTASSIUM SALT

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OXONIC ACID POTASSIUM SALT Basic information

Product Name:
OXONIC ACID POTASSIUM SALT
Synonyms:
  • 1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt
  • 5-azaoroticacid,potassiumsalt
  • 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt, Allantoxanic acid
  • (OXO)Oteracil potassium
  • Potassium 4,6-dioxo-1H-1,3,5-triazine-2-carboxylate
  • Potassium s-triazine-2,4-dione-6-carboxylate
  • 1,4,5,6-Tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid potassium salt
  • Allantoxanic acid potassium
CAS:
2207-75-2
MF:
C4H2KN3O4
MW:
195.17
EINECS:
218-627-5
Product Categories:
  • Anti-cancer&immunity
  • oncology
  • Classes of Metal Compounds
  • K (Potassium) Compounds (excluding simple potassium salts)
  • Typical Metal Compounds
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Anticancer
Mol File:
2207-75-2.mol
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OXONIC ACID POTASSIUM SALT Chemical Properties

Melting point:
300 °C(lit.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
form 
Powder
color 
White
Water Solubility 
Soluble in hot water.
CAS DataBase Reference
2207-75-2(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
RR4580000
HS Code 
29349990

MSDS

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OXONIC ACID POTASSIUM SALT Usage And Synthesis

Description

Oxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; ), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats. Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas.

Chemical Properties

Off-White Solid

Uses

Antitumor effect potentiator and antitumor agent

Uses

Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.

Uses

Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.

Definition

ChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity.

OXONIC ACID POTASSIUM SALTSupplier

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