3-CHLORO-6-METHOXYPYRIDAZINE Chemical Properties

Melting point:

84-85 °C(lit.)

Boiling point:

285℃

Density 

1.292

Flash point:

126℃

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

pka

0.74±0.10(Predicted)

color 

White to Almost white

BRN 

118854

InChI

InChI=1S/C5H5ClN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3

InChIKey

XBJLKXOOHLLTPG-UHFFFAOYSA-N

SMILES

C1(Cl)=NN=C(OC)C=C1

CAS DataBase Reference

1722-10-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933998090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-CHLORO-6-METHOXYPYRIDAZINE Usage And Synthesis

Uses

3-Chloro-6-methoxypyridazine was used in the preparation of number of α-aryl-α-(pyridazin-3-yl)-acetonitriles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 1466, 1995 DOI: 10.1021/jo00110a059

General Description

3-Chloro-6-methoxypyridazine undergoes regioselective metallation using various lithium alkylamides, temperatures and solvents (THF and ether). It was lithiated using lithium 2,2,6,6-tetramethylpiperidide during the synthesis of minaprine.

3-CHLORO-6-METHOXYPYRIDAZINE(1722-10-7)Related Product Information

• 3-Chloro-6-methylpyridazine
• 6-chloro-N-(propan-2-yl)pyridazin-3-amine
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• 3-Chloro-6-chloromethylpyridazine
• 3-chloro-6-isopropylpyridazine
• 3-CHLORO-6-PROPYLOXYPYRIDAZINE
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• 3-CHLORO-6-PHENYLPYRIDAZINE
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• 3-CHLORO-6-ISOPROPOXYPYRIDAZINE
• 3-CHLORO-6-ETHOXYPYRIDAZINE
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