3-CHLORO-6-METHOXYPYRIDAZINE

Product Name: 3-CHLORO-6-METHOXYPYRIDAZINE
CAS No.: 1722-10-7
Chemical Name: 3-CHLORO-6-METHOXYPYRIDAZINE
Synonyms: NSC 69819;NSC 522667;TIMTEC-BB SBB004124;SPECS AC-907/25014054;3-Chloro-6-methoxypyrazine;6-Chloro-3-methoxypyridazine;3-Methoxy-6-chloropyridazine;3-CHLORO-6-METHOXYPYRIDAZINE;3-Chloro-6-methoxy-1,2-diazine;pyridazine, 3-chloro-6-methoxy-
CBNumber: CB9437764
Molecular Formula: C5H5ClN2O
Formula Weight: 144.56
MOL File: 1722-10-7.mol

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3-CHLORO-6-METHOXYPYRIDAZINE Property

Melting point:: 84-85 °C(lit.)
Boiling point:: 285℃
Density: 1.292
Flash point:: 126℃
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 0.74±0.10(Predicted)
color: White to Almost white
BRN: 118854
InChI: InChI=1S/C5H5ClN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3
InChIKey: XBJLKXOOHLLTPG-UHFFFAOYSA-N
SMILES: C1(Cl)=NN=C(OC)C=C1
CAS DataBase Reference: 1722-10-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 108596
Product name: 3-Chloro-6-methoxypyridazine
Purity: 95%
Packaging: 5g
Price: $111
Updated: 2023/01/07

TCI Chemical

Product number: C2376
Product name: 3-Chloro-6-methoxypyridazine
Purity: >97.0%(GC)
Packaging: 5g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: C2376
Product name: 3-Chloro-6-methoxypyridazine
Purity: >97.0%(GC)
Packaging: 25g
Price: $298
Updated: 2025/07/31

TRC

Product number: C368103
Product name: 3-Chloro-6-methoxypyridazine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: W3748
Product name: 3-Chloro-6-methoxypyridazine
Packaging: 5g
Price: $19
Updated: 2021/12/16

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3-CHLORO-6-METHOXYPYRIDAZINE Chemical Properties,Usage,Production

Uses

3-Chloro-6-methoxypyridazine was used in the preparation of number of α-aryl-α-(pyridazin-3-yl)-acetonitriles.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 1466, 1995 DOI: 10.1021/jo00110a059

General Description

3-Chloro-6-methoxypyridazine undergoes regioselective metallation using various lithium alkylamides, temperatures and solvents (THF and ether). It was lithiated using lithium 2,2,6,6-tetramethylpiperidide during the synthesis of minaprine.

Synthesis

141-30-0

124-41-4

1722-10-7

A methanolic solution of 0.5 M sodium methanolate (NaOMe/MeOH, 7.4 mL, 3.69 mmol) was slowly added dropwise to a solution of anhydrous tetrahydrofuran (12 mL) containing 3,6-dichloropyridazine (500 mg, 3.36 mmol), and the reaction mixture was stirred for 1 h at room temperature. Subsequently, the reaction was quenched by the addition of water. The reaction mixture was extracted with ethyl acetate and the organic phases were combined. The organic phase was washed with saturated aqueous sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography to afford 6-methoxy-3-chloropyridazine (436 mg, 90% yield) as a white solid.1H NMR (400 MHz, CDCl3) δ 4.12 (s, 3H), 6.98 (d, J = 9.2 Hz, 1H), 7.38 (d, J = 9.2 Hz, 1H); 13C NMR (100 MHz, CDCl3) δ 55.5 (d, J = 9.2 Hz, 1H). CDCl3) δ 55.2, 119.9, 130.6, 150.9, 164.2.

References

[1] Journal of Heterocyclic Chemistry, 2005, vol. 42, # 4, p. 509 - 513
[2] Patent: US2010/261727, 2010, A1. Location in patent: Page/Page column 31
[3] ACS Chemical Neuroscience, 2017, vol. 8, # 11, p. 2374 - 2380
[4] Journal of Heterocyclic Chemistry, 2013, vol. 50, # 5, p. 1165 - 1173
[5] Journal of the American Chemical Society, 1959, vol. 81, p. 6511,6512

3-CHLORO-6-METHOXYPYRIDAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-6-METHOXYPYRIDAZINE Suppliers

Americas 1 China 143 Europe 1 France 1 Germany 3 India 11 Japan 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 10 United States 27 Global 201

J & K SCIENTIFIC LTD.

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View Lastest Price from 3-CHLORO-6-METHOXYPYRIDAZINE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 3-Chloro-6-methoxypyridazine 1722-10-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Shanghai Rlavie Technology Co ltd

Product: 3-Chloro-6-methoxypyridazine 1722-10-7
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 300kgs/month
Release date: 2021-11-14

Dideu Industries Group Limited

Product: 3-CHLORO-6-METHOXYPYRIDAZINE 1722-10-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-02

1722-10-7, 3-CHLORO-6-METHOXYPYRIDAZINERelated Search:

3-Chloro-6-methylpyridazine 6-chloro-N-(propan-2-yl)pyridazin-3-amine 3-chloro-6-(chloroMethyl)pyridazine hydrochloride 3-Chloro-6-trifluoromethyl-pyridazine 3-Chloro-6-chloromethylpyridazine 3-chloro-6-isopropylpyridazine 3-CHLORO-6-PROPYLOXYPYRIDAZINE 3-Chloro-6-hydrazinopyridazine 3-Chloro-6-(1H-pyrazol-1-yl)pyridazine 6-Chloro-N-ethylpyridazin-3-amine 3-Chloro-6-iodopyridazine 6-CHLOROPYRIDAZINE-3-THIOL 3-CHLORO-6-PHENYLPYRIDAZINE 3-(TERT-BUTOXY)-6-CHLOROPYRIDAZINE 3-CHLORO-6-PHENOXYPYRIDAZINE 3-CHLORO-6-ISOPROPOXYPYRIDAZINE 3-CHLORO-6-ETHOXYPYRIDAZINE 2-Chloro-10-methyl-3,4-diazaphenoxazine

3-CHLORO-6-METHOXYPYRIDAZINE

SPECS AC-907/25014054

TIMTEC-BB SBB004124

3-Methoxy-6-chloropyridazine

6-Chloro-3-methoxypyridazine

pyridazine, 3-chloro-6-methoxy-

3-Chloro-6-methoxypyridazine,97%

NSC 522667

NSC 69819

3-Chloro-6-methoxy-1,2-diazine

3-Chloro-6-methoxypyridazine 95%

JR-8338, 3-Chloro-6-methoxypyridazine, 97%

3-Chloro-6-methoxypyridazine &gt

3-Chloro-6-methoxypyrazine

3-CHLORO-6-METHOXYPYRIDAZINE ISO 9001：2015 REACH

1722-10-7

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