1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Chemical Properties

Melting point:

109-111°C

Boiling point:

369.5±37.0 °C(Predicted)

Density 

1.198±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

7.41±0.42(Predicted)

form 

Solid

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HazardClass 

IRRITANT

HS Code 

29339900

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE Usage And Synthesis

Chemical Properties

Red solid

Uses

1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases.

1-METHYL-4-(4-NITROPHENYL)PIPERAZINE(16155-03-6)Related Product Information

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