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Hederacoside C

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Hederacoside C Basic information

Product Name:
Hederacoside C
Synonyms:
  • KIZUTA SAPONIN K(12
  • HEDERACOSIDE C WITH HPLC
  • Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl]oxy]-23-hydroxy-, O-6-deoxy-alpha-l-mannopyranosyl-(1->4)-O-beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranosyl ester, (3beta,4alpha)-
  • kalopanax saponin B
  • HEDERACOSIDE C
  • (3beta,4alpha)-3-[[2-O-(6-Deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid O-6-deoxy-alpha-l-mannopyranosyl-(1->4)-O-beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranosyl ester
  • Hederacoside c, froM Hedera nepalensis
  • 4)-O-b-D-glucopyranosyl-(1®
CAS:
14216-03-6
MF:
C59H96O26
MW:
1221.38
EINECS:
238-072-2
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • AliphaticAnalytical Standards
  • Herbal DrugsChromatography
  • Alcohols
  • Chemical Class
  • EstersAlphabetic
  • H
  • HA -HTChemical Class
  • Heterocyclics
  • Life Sciences Standards
  • Natural Compounds
  • Natural CompoundsChemical Class
  • Natural Terpene StandardsChemical Class
  • Oxygen containingChemical Class
  • Polyhydroxy compoundsMore...Close...
Mol File:
14216-03-6.mol
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Hederacoside C Chemical Properties

Melting point:
222 °C (dec.)(lit.)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Sparingly)
pka
12.50±0.70(Predicted)
form 
Solid
color 
White to Pale Beige
BRN 
4229541
Stability:
Hygroscopic
InChIKey
RYHDIBJJJRNDSX-MCGLQMIESA-N
LogP
4.520 (est)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-24/25
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
F 
10-23
HS Code 
29389090

MSDS

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Hederacoside C Usage And Synthesis

Chemical Properties

White powder

Uses

Hederacoside C is a Hedera helix leaf which has been used in botanical drug formulations to treat acute respiratory infection and bronchitis. Anti-myocardial.

Uses

solubilizer, bio-availability enhancer in oral suspensions, capsules

Definition

ChEBI: A triterpenoid saponin with hederagenin as the aglycone part. It has been isolated from the stem bark of Kalopanax pictus.

in vivo

Hederacoside C (0.625, 1.25, 2.5 mg/kg, intraperitoneally injected for 7 consecutive days) can alleviate TNBS-induced enteritis[1].
Hederacoside C (5, 10, 50 mg/kg, intraperitoneally injected for 3 consecutive times for 8 h) can attenuate the breast lesions caused by Staphylococcus aureus[2].

Animal Model:TNBS-induced colitis in rat[1]
Dosage:0.625, 1.25, 2.5 mg/kg
Administration:i.p. for 7 days
Result:Decreased the levels of inflammatory cytokines, including TNF-α, IL-6, IL-1β, CXCL-1, CXCL-2, and CXCL-5.
Reduced cell apoptosis in TNBS-induced colitis.
Reduced Bax/Bcl-2 ratio, cleaved caspase 3, and p53 protein levels in a dose-dependent manner.

Hederacoside CSupplier

Shanghai YuanYe Biotechnology Co., Ltd. Gold
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Chengdu Biopurify Phytochemicals Ltd. Gold
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+86-028-82633397 18982077548
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Chengdu Nakeli Biotechnology Co., Ltd. Gold
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028-61983833 19138982515
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Chengdu Push Bio-Technology Co., Ltd. Gold
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028-028-85370565-229-229 18080489829
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18080489829@163.com
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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jkinfo@jkchemical.com
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