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2-(4-NITROPHENYL)BUTYRIC ACID

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2-(4-NITROPHENYL)BUTYRIC ACID Basic information

Product Name:
2-(4-NITROPHENYL)BUTYRIC ACID
Synonyms:
  • 2-(p-nitrophenyl)-butyricaci
  • 2-(p-nitrophenyl)butyricacid
  • alpha-ethyl-4-nitro-benzeneaceticaci
  • alpha-ethyl-4-nitrobenzeneaceticacid
  • ALPHA-ETHYL-4-NITROPHENYLACETIC ACID
  • A-ETHYL-4-NITROBENZONIC ACID
  • 2-(4-NITROPHENYL)BUTYRIC ACID
  • α-(p-Nitro-phenyl)butyric acid
CAS:
7463-53-8
MF:
C10H11NO4
MW:
209.2
EINECS:
231-256-3
Mol File:
7463-53-8.mol
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2-(4-NITROPHENYL)BUTYRIC ACID Chemical Properties

Melting point:
122-123 °C
Boiling point:
371.2±25.0 °C(Predicted)
Density 
1.287±0.06 g/cm3(Predicted)
pka
3.91±0.10(Predicted)
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2-(4-NITROPHENYL)BUTYRIC ACID Usage And Synthesis

Uses

2-(4-Nitrophenyl)butyric acid is a key intermediate in the synthesis of indobufen, a new generation of anti-platelet aggregation agents.

Synthesis

Synthesis of 2-(4-nitrophenyl)butyric acid, using α-phenylbutyronitrile as the starting material, to produce 2-(4-nitrophenyl)butyronitrile by nitration reaction, and then by hydrolysis reaction to produce 2-(4-nitrophenyl)butyric acid.

2-(4-NITROPHENYL)BUTYRIC ACID Preparation Products And Raw materials

Raw materials

MethanolSulfuric acid DichloromethaneAcetic acid glacialNitric acidBromoethaneBenzeneacetonitrile2-Phenylbutyric acid

2-(4-NITROPHENYL)BUTYRIC ACIDSupplier

Shenyang Kelaishen Chemical Products Co., Ltd. Gold
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029-84536388 18717328141
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2-(4-NITROPHENYL)BUTYRIC ACID(7463-53-8)Related Product Information